SETDB1 Antibody
Product Specifications
Background
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
NCBI Gene ID
9869
Swiss Prot
Q15047
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-397 of human SETDB1 (NP_001230420.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 210kDa
Fragment
IgG
Symbol
SETDB1
Positive Control 2
MCF7
Positive Control 3
DU145
Positive Control 4
HL-60
Positive Control 5
Jurkat
Positive Control 6
293T
NCBI Official Name
SET domain, bifurcated 1
NCBI Organism
Homo sapiens
Other Product Names
SETDB1, H3-K9-HMTase4, ESET, KMT1E, H3-K9-HMTase 4, KG1T, SET domain, bifurcated 1, SET domain bifurcated 1, KIAA0067, Lysine N-methyltransferase 1E
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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