KEAP1 Antibody
Product Specifications
Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
NCBI Gene ID
9817
Swiss Prot
Q14145
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 325-624 of human KEAP1 (NP_036421.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
KEAP1
Positive Control 2
U-87MG
Positive Control 3
Jurkat
NCBI Official Name
Kelch-like ECH-associated protein 1
NCBI Organism
Homo sapiens
Other Product Names
KEAP1 Antibody: INrf2, KLHL19, INRF2, KIAA0132, Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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