PRPF4 Antibody

Product Specifications

Background

The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

9128

Swiss Prot

O43172

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PRPF4 (NP_004688.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 58kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PRPF4

Positive Control 2

SKOV3

Positive Control 3

SW480

Positive Control 4

DU145

Positive Control 5

MCF7

Positive Control 6

Mouse spleen

NCBI Official Name

Pre-mRNA processing factor 4

NCBI Organism

Homo sapiens

Other Product Names

HPRP4, HPRP4P, PRP4, Prp4p, RP7SNRNP6U4/U6 small nuclear ribonucleoprotein Prp4, PRP4 homolog, PRP4 pre-mRNA processing factor 4 homolog, PRP4/STK/WD splicing factor, U4/U6 snRNP 60 kDa protein, WD splicing factor Prp4