DEDD Antibody
Product Specifications
Background
This gene encodes a protein that contains a death effector domain (DED) . DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
9191
Swiss Prot
O75618
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human DEDD (NP_001034801.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Symbol
DEDD
NCBI Official Name
Death effector domain-containing protein
NCBI Organism
Homo sapiens
Other Product Names
Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD, DEDPRO1, DEFT
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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