CDC7 Antibody

Product Specifications

Background

This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.

NCBI Gene ID

8317

Swiss Prot

O00311

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CDC7

Positive Control 2

HepG2

Positive Control 3

THP-1

NCBI Official Name

Cell division cycle 7

NCBI Organism

Homo sapiens

Other Product Names

CDC7L1, HsCDC7, Hsk1, huCDC7, cell division cycle 7-related protein kinase, CDC7 (cell division cycle 7, S. cerevisiae, homolog) -like 1, CDC7-related kinase, cell division cycle 7 homolog, cell division cycle 7-like protein 1, epididymis secretory sperm binding protein