QDPR Antibody
Product Specifications
Background
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
NCBI Gene ID
5860
Swiss Prot
P09417
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human QDPR (NP_000311.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 26kDa
Fragment
IgG
Symbol
QDPR
Positive Control 2
Mouse kidney
Positive Control 3
Mouse brain
Positive Control 4
Rat liver
Positive Control 5
HL-60
Positive Control 6
BT-474
NCBI Official Name
Dihydropteridine reductase
NCBI Organism
Homo sapiens
Other Product Names
Dihydropteridine reductase, HDHPR, Quinoid dihydropteridine reductase, QDPR, DHPR
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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