PNMT Antibody
Product Specifications
Background
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline) . The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
5409
Swiss Prot
P11086
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human PNMT (NP_002677.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 31-34kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PNMT
Positive Control 2
Mouse liver
Positive Control 3
Mouse heart
NCBI Official Name
Phenylethanolamine N-methyltransferase
NCBI Organism
Homo sapiens
Other Product Names
PENTase, PNMT, phenylethanolamine N-methyltransferase, noradrenaline N-methyltransferase, phenylethanolamine N-methylase
Tested Applications
WB
Physical Properties
Liquid
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