RFC4 Antibody
Product Specifications
Background
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
NCBI Gene ID
5984
Swiss Prot
P35249
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Symbol
RFC4
Positive Control 2
SW480
Positive Control 3
22Rv1
Positive Control 4
SW620
Positive Control 5
K-562
Positive Control 6
HepG2
NCBI Official Name
Replication factor C (activator 1) 4, 37kDa
NCBI Organism
Homo sapiens
Other Product Names
RFC4, A1, MGC27291, RFC37
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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