PSMB2 Antibody
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
NCBI Gene ID
5690
Swiss Prot
P49721
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PSMB2 (NP_002785.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 23kDa
Fragment
IgG
Symbol
PSMB2
Positive Control 2
U-937
Positive Control 3
K-562
Positive Control 4
U-87MG
Positive Control 5
HT-29
Positive Control 6
HeLa
NCBI Official Name
Proteasome (prosome, macropain) subunit, beta type, 2
NCBI Organism
Homo sapiens
Other Product Names
PSMB2, HC7-I, MGC104215, MGC126885
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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