LBR Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

NCBI Gene ID

3930

Swiss Prot

Q14739

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human LBR (NP_002287.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

22Rv1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 68kDa

Fragment

IgG

Symbol

LBR

Positive Control 2

Mouse eye

Positive Control 3

Mouse spleen

Positive Control 4

Mouse lung

NCBI Official Name

Lamin B receptor

NCBI Organism

Homo sapiens

Other Product Names

C14SR, DHCR14B, LMN2R, PHA, PHASK, TDRD18, delta (14) -sterol reductase, 3-beta-hydroxysterol Delta (14) -reductase, C-14 sterol reductase, delta-14-SR, integral nuclear envelope inner membrane protein, sterol C14-reductase, tudor domain containing 18