CPE Antibody
Product Specifications
Background
This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.
NCBI Gene ID
1363
Swiss Prot
P16870
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 257-476 of human CPE (NP_001864.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 53-55kDa
Fragment
IgG
Symbol
CPE
Positive Control 2
MCF7
Positive Control 3
Mouse brain
Positive Control 4
Mouse kidney
NCBI Official Name
Carboxypeptidase E
NCBI Organism
Homo sapiens
Other Product Names
CPE
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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