NPC2 Antibody

Product Specifications

Background

This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.

NCBI Gene ID

10577

Swiss Prot

P61916

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-151 of human NPC2 (NP_006423.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse lung

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 19kDa

Fragment

IgG

Symbol

NPC2

NCBI Official Name

Niemann-Pick disease, type C2

NCBI Organism

Homo sapiens

Other Product Names

NPC2, tissue-specific secretory protein, NP-C2, Niemann-Pick disease, type C2, MGC1333, HE1, epididymal secretory protein E1, epididymal secretory protein, epididymal protein 1, EDDM1