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COTL1 Antibody

Product Specifications

Background

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

NCBI Gene ID

23406

Swiss Prot

Q14019

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human COTL1 (NP_066972.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 14kDa

Fragment

IgG

Symbol

COTL1

Positive Control 2

293T

Positive Control 3

U-251MG

Positive Control 4

HeLa

Positive Control 5

Mouse lung

Positive Control 6

Mouse kidney

NCBI Official Name

Coactosin-like protein

NCBI Organism

Homo sapiens

Other Product Names

Coactosin-like protein, COTL1, CLP

Tested Applications

WB, IHC

Physical Properties

Liquid

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