SGCA Antibody
Product Specifications
Background
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6442
Swiss Prot
Q16586
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-290 of human SGCA (NP_000014.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SGCA
Positive Control 2
LO2
Positive Control 3
293T
Positive Control 4
Mouse skeletal muscle
Positive Control 5
Mouse heart
Positive Control 6
Rat skeletal muscle
NCBI Official Name
Alpha-sarcoglycan
NCBI Organism
Homo sapiens
Other Product Names
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2, SGCA, ADL, DAG2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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