PKD2 Antibody
Product Specifications
Background
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
NCBI Gene ID
5311
Swiss Prot
Q13563
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PKD2 (NP_000288.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
PKD2
Positive Control 2
MCF7
Positive Control 3
Mouse kidney
NCBI Official Name
Polycystic kidney disease 2 (autosomal dominant)
NCBI Organism
Homo sapiens
Other Product Names
Polycystwin, polycystin 2, PKD4, PC2, MGC138468, MGC138466, APKD2, polycystic kidney disease 2 (autosomal dominant), PKD2, Pc-2, TRPP2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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