PARD6A Antibody

Product Specifications

Background

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

NCBI Gene ID

50855

Swiss Prot

Q9NPB6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human PARD6A

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

SW620

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 47kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PARD6A

Positive Control 2

HT-29

Positive Control 3

Jurkat

Positive Control 4

U-251MG

Positive Control 5

Raji

Positive Control 6

Mouse testis

NCBI Official Name

Par-6 family cell polarity regulator alpha

NCBI Organism

Homo sapiens

Other Product Names

PARD6A, PAR-6, TAX40, PAR-6A, TIP-40, PAR6alpha, par-6 partitioning defective 6 homolog alpha (C.elegans), Tax interaction protein 40, par-6 (partitioning defective 6, C.elegans) homolog alpha, PAR6A