Bcl2 Antibody
Product Specifications
Background
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
596
Swiss Prot
P10415
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 81-131 of human Bcl2 (NP_000624.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Symbol
BCL2
Positive Control 2
HL-60
Positive Control 3
U-937
NCBI Official Name
B-cell CLL/lymphoma 2
NCBI Organism
Homo sapiens
Other Product Names
Bcl-2 Antibody: Bcl-2, PPP1R50, Apoptosis regulator Bcl-2
Tested Applications
WB, IF, IP
Physical Properties
Liquid
Curated Selection
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