MAPRE1 Antibody
Product Specifications
Background
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.
NCBI Gene ID
22919
Swiss Prot
Q15691
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 134-268 of human MAPRE1 (NP_036457.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
B-cell
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 34kDa
Fragment
IgG
Symbol
MAPRE1
Positive Control 2
U-87MG
Positive Control 3
LO2
Positive Control 4
HT-29
Positive Control 5
NIH/3T3
Positive Control 6
Mouse lung
NCBI Official Name
Microtubule-associated protein RP/EB family member 1
NCBI Organism
Homo sapiens
Other Product Names
Microtubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1, EB1, MAPRE1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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