SDHA Antibody

Product Specifications

Background

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

6389

Swiss Prot

P31040

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 385-664 of human SDHA (NP_004159.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

SDHA

Positive Control 2

U-251MG

Positive Control 3

PC-3

Positive Control 4

MCF7

Positive Control 5

Mouse liver

Positive Control 6

Mouse stomach

NCBI Official Name

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

NCBI Organism

Homo sapiens

Other Product Names

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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