EEF1D Antibody

Product Specifications

Background

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.

NCBI Gene ID

1936

Swiss Prot

P29692

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human EEF1D (NP_001123529.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 38kDa

Fragment

IgG

Symbol

EEF1D

Positive Control 2

PC-3

Positive Control 3

BT-474

Positive Control 4

Jurkat

Positive Control 5

A-549

Positive Control 6

Mouse spleen

NCBI Official Name

Eukaryotic translation elongation factor 1 delta

NCBI Organism

Homo sapiens

Other Product Names

EF-1D, EF1D, FP1047, elongation factor 1-delta, EF-1-delta, antigen NY-CO-4, eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)