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BRD4 Antibody

Product Specifications

Background

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t (15;19) (q13; p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

NCBI Gene ID

23476

Swiss Prot

O60885

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human BRD4

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 200kDa

Fragment

IgG

Symbol

BRD4

Positive Control 2

HeLa

Positive Control 3

NIH/3T3

NCBI Official Name

Bromodomain containing 4

NCBI Organism

Homo sapiens

Other Product Names

BRD4, CAP, HUNKI, MCAP, HUNK1

Tested Applications

WB, IF

Physical Properties

Liquid

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