CD18 Antibody

Product Specifications

Background

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

3689

Swiss Prot

P05107

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-170 of human CD18 (NP_000202.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

U-937

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 100kDa

Fragment

IgG

Symbol

ITGB2

Positive Control 2

Mouse thymus

Positive Control 3

Mouse lung

Positive Control 4

Rat thymus

NCBI Official Name

Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

NCBI Organism

Homo sapiens

Other Product Names

Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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