CD151 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

NCBI Gene ID

977

Swiss Prot

P48509

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 113-221 of human CD151 (NP_001034579.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse skeletal muscle

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 28kDa

Fragment

IgG

Symbol

CD151

NCBI Official Name

CD151 molecule (Raph blood group)

NCBI Organism

Homo sapiens

Other Product Names

GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24, CD151 antigen, CD151 antigen (Raph blood group), hemidesmosomal tetraspanin CD151, membrane glycoprotein SFA-1, platelet surface glycoprotein gp27, platelet-endothelial cell tetraspan antigen 3, platelet-endothelial tetraspan antigen 3, tetraspanin-24, tspan-24