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IDS Antibody

Product Specifications

Background

This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

NCBI Gene ID

3423

Swiss Prot

P22304

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 34-290 of human IDS (NP_006114.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 76kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

IDS

Positive Control 2

A-549

Positive Control 3

HT-1080

Positive Control 4

Mouse kidney

Positive Control 5

Rat kidney

NCBI Official Name

Iduronate 2-sulfatase

NCBI Organism

Homo sapiens

Other Product Names

IDS, iduronate 2-sulfatase (Hunter syndrome), MPS2, SIDS, iduronate-2-sulfatase

Tested Applications

WB

Physical Properties

Liquid

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