IDS Antibody
Product Specifications
Background
This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
NCBI Gene ID
3423
Swiss Prot
P22304
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 34-290 of human IDS (NP_006114.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 76kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IDS
Positive Control 2
A-549
Positive Control 3
HT-1080
Positive Control 4
Mouse kidney
Positive Control 5
Rat kidney
NCBI Official Name
Iduronate 2-sulfatase
NCBI Organism
Homo sapiens
Other Product Names
IDS, iduronate 2-sulfatase (Hunter syndrome), MPS2, SIDS, iduronate-2-sulfatase
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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