BUB1B Antibody
Product Specifications
Background
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
NCBI Gene ID
701
Swiss Prot
O60566
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BUB1B (NP_001202.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa/120kDa
Fragment
IgG
Symbol
BUB1B
Positive Control 2
HeLa
Positive Control 3
Jurkat
Positive Control 4
HT-29
Positive Control 5
A-549
Positive Control 6
COS-7
NCBI Official Name
BUB1 mitotic checkpoint serine/threonine kinase B
NCBI Organism
Homo sapiens
Other Product Names
BUB1B, Bub1A, BUBR1, HBUBR1, Protein SSK1, SSK1, BUB1beta, MAD3L
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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