SUMF2 Antibody

Product Specifications

Background

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly) . The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

NCBI Gene ID

25870

Swiss Prot

Q8NBJ7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 45-320 of human SUMF2 (NP_056226.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 34kDa

Fragment

IgG

Symbol

SUMF2

Positive Control 2

A-549

Positive Control 3

HepG2

Positive Control 4

BxPC-3

NCBI Official Name

Sulfatase modifying factor 2

NCBI Organism

Homo sapiens

Other Product Names

PFGE, inactive C-alpha-formylglycine-generating enzyme 2, C-alpha-formyglycine-generating enzyme 2, C-alpha-formylglycine-generating enzyme 2, epididymis secretory sperm binding protein, paralog of formylglycine-generating enzyme, paralog of the formylglycine-generating enzyme