FLRT2 Antibody
Product Specifications
Background
This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
NCBI Gene ID
23768
Swiss Prot
O43155
Host
Rabbit
Reactivity
Mouse
Immunogen
A synthetic peptide of Human FLRT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
FLRT2
NCBI Official Name
Fibronectin leucine rich transmembrane protein 2
NCBI Organism
Homo sapiens
Other Product Names
Leucine-rich repeat transmembrane protein FLRT2, fibronectin-like domain-containing leucine-rich transmembrane protein 2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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