MAP4K2 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
NCBI Gene ID
5871
Swiss Prot
Q12851
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 551-820 of human MAP4K2 (NP_004570.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Symbol
MAP4K2
Positive Control 2
A-549
Positive Control 3
C6
Positive Control 4
Raji
Positive Control 5
HeLa
Positive Control 6
Mouse lung
NCBI Official Name
Mitogen-activated protein kinase kinase kinase kinase 2
NCBI Organism
Homo sapiens
Other Product Names
MAP4K2, BL44, GCK, RAB8IP
Tested Applications
WB, IHC
Physical Properties
Liquid
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