XRCC4 Antibody
Product Specifications
Background
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants.
NCBI Gene ID
7518
Swiss Prot
Q13426
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human XRCC4 (NP_071801.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Symbol
XRCC4
Positive Control 2
MCF7
Positive Control 3
K562
Positive Control 4
HeLa
Positive Control 5
Mouse thymus
Positive Control 6
Mouse heart
NCBI Official Name
DNA repair protein XRCC4
NCBI Organism
Homo sapiens
Other Product Names
DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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