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SOSTDC1 Antibody

Product Specifications

Background

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

NCBI Gene ID

25928

Swiss Prot

Q6X4U4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 115-206 of human SOSTDC1 (NP_056279.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=16-546

Calculated Molecular Weight

Observed: 26kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SOSTDC1

Positive Control 2

Mouse brain

Positive Control 3

Mouse kidney

Positive Control 4

Rat brain

NCBI Official Name

Sclerostin domain-containing protein 1

NCBI Organism

Homo sapiens

Other Product Names

Sclerostin domain-containing protein 1, Ectodermal BMP inhibitor, Ectodin, Uterine sensitization-associated gene 1 protein, USAG-1, SOSTDC1, USAG1

Tested Applications

WB

Physical Properties

Liquid

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