ACMSD Antibody
Product Specifications
Background
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS) . ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
NCBI Gene ID
130013
Swiss Prot
Q8TDX5
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human ACMSD (NP_612199.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 38kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ACMSD
Positive Control 2
Mouse liver
Positive Control 3
Rat kidney
NCBI Official Name
Aminocarboxymuconate semialdehyde decarboxylase
NCBI Organism
Homo sapiens
Other Product Names
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, picolinate carboxylase
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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