MRPL17 Antibody
Product Specifications
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
NCBI Gene ID
63875
Swiss Prot
Q9NRX2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 86-175 of human MRPL17 (NP_071344.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 25kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MRPL17
Positive Control 2
MCF7
Positive Control 3
Mouse kidney
NCBI Official Name
Mitochondrial ribosomal protein L17
NCBI Organism
Homo sapiens
Other Product Names
L17mt, LIP2, MRP-L17, MRP-L26, RPL17L, RPML26, 39S ribosomal protein L17, mitochondrial, LYST-interacting protein 2, LYST-interacting protein LIP2, mitochondrial large ribosomal subunit protein bL17m
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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