PRMT5 Antibody
Product Specifications
Background
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
10419
Swiss Prot
O14744
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 40-140 of human PRMT5 (NP_006100.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Symbol
PRMT5
Positive Control 2
HepG2
Positive Control 3
HeLa
Positive Control 4
NIH/3T3
Positive Control 5
PC-12
Positive Control 6
COS-1
NCBI Official Name
Protein arginine methyltransferase 5
NCBI Organism
Homo sapiens
Other Product Names
PRMT5, JBP1, SKB1, IBP72, SKB1Hs, HRMT1L5
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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