DYNLRB1 Antibody
Product Specifications
Background
This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
NCBI Gene ID
83658
Swiss Prot
Q9NP97
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-923
Calculated Molecular Weight
Observed: 20kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
DYNLRB1
Positive Control 2
Mouse brain
NCBI Official Name
Dynein light chain roadblock-type 1
NCBI Organism
Homo sapiens
Other Product Names
BITH, BLP, DNCL2A, DNLC2A, ROBLD1, dynein light chain roadblock-type 1, ROBL/LC7-like 1, bithoraxoid-like protein, dynein, cytoplasmic, light polypeptide 2A, dynein-associated protein Km23, roadblock domain-containing protein 1
Tested Applications
WB
Physical Properties
Liquid
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