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TP53BP2 Antibody

Product Specifications

Background

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7159

Swiss Prot

Q13625

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human TP53BP2 (NP_001026855.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 170kDa

Fragment

IgG

Symbol

TP53BP2

Positive Control 2

OVCAR3

Positive Control 3

K562

Positive Control 4

A-549

NCBI Official Name

Tumor protein p53 binding protein, 2

NCBI Organism

Homo sapiens

Other Product Names

TP53BP2, BBP, 53BP2, ASPP2, P53BP2, PPP1R13A

Tested Applications

WB, IHC

Physical Properties

Liquid

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