TPH2 Antibody
Product Specifications
Background
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
NCBI Gene ID
121278
Swiss Prot
Q8IWU9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TPH2 (NP_775489.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54-56kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TPH2
Positive Control 2
SH-SY5Y
Positive Control 3
Mouse brain
Positive Control 4
Rat brain
NCBI Official Name
Tryptophan hydroxylase 2
NCBI Organism
Homo sapiens
Other Product Names
TPH2, NTPH, ADHD7
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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