PRRG2 Antibody

Product Specifications

Background

The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5639

Swiss Prot

O14669

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human PRRG2 (NP_001303264.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 23kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PRRG2

Positive Control 2

Mouse lung

Positive Control 3

Rat liver

Positive Control 4

Rat lung

NCBI Official Name

Proline rich and Gla domain 2

NCBI Organism

Homo sapiens

Other Product Names

PRGP2, transmembrane gamma-carboxyglutamic acid protein 2, proline rich Gla (G-carboxyglutamic acid) 2, proline-rich Gla (G-carboxglutamic acid) polypeptide 2, proline-rich Gla (G-carboxyglutamic acid) polypeptide 2, proline-rich Gla protein 2, proline-rich gamma-carboxyglutamic acid protein 2