MAP2K6 Antibody

Product Specifications

Background

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

NCBI Gene ID

5608

Swiss Prot

P52564

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MAP2K6 (NP_002749.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Innate Immunity, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 37kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MAP2K6

Positive Control 2

Mouse brain

Positive Control 3

Rat brain

NCBI Official Name

Mitogen-activated protein kinase kinase 6

NCBI Organism

Homo sapiens

Other Product Names

MAP2K6, Mapk kinase 6, MAPK/ERK kinase 6, MEK6, SAPKK3, SAPKK-3, MAP kinase kinase 6, MAPKK6, PRKMK6, MAPKK 6, MEK 6, MKK6, SAPK kinase 3, SKK3

Tested Applications

Physical Properties

Liquid

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