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NDC80 Antibody

Product Specifications

Background

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

NCBI Gene ID

10403

Swiss Prot

O14777

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human NDC80 (NP_006092.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

Affinity purification

Positive Control

K-562

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 74kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NDC80

Positive Control 2

Lovo

Positive Control 3

MCF7

Positive Control 4

22Rv1

Positive Control 5

THP-1

Positive Control 6

293T

NCBI Official Name

NDC80 kinetochore complex component

NCBI Organism

Homo sapiens

Other Product Names

HEC, highly expressed in cancer, rich in leucine heptad repeats, HEC1, HEC-1, HEC, KNTC2

Tested Applications

WB

Physical Properties

Liquid

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