BTD Antibody
Product Specifications
Background
The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.
NCBI Gene ID
686
Swiss Prot
P43251
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 284-543 of human BTD (NP_000051.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65-70kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
BTD
Positive Control 2
Mouse liver
Positive Control 3
Rat kidney
NCBI Official Name
Biotinidase
NCBI Organism
Homo sapiens
Other Product Names
BTD, biotinidase, OTTHUMP00000160300, OTTHUMP00000209134, OTTHUMP00000209135, OTTHUMP00000209138, biotinase
Tested Applications
WB
Physical Properties
Liquid
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