MDFI Antibody
Product Specifications
Background
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
NCBI Gene ID
4188
Swiss Prot
Q99750
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MDFI (NP_005577.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
Mouse heart
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 35kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MDFI
Positive Control 2
Rat heart
NCBI Official Name
MyoD family inhibitor
NCBI Organism
Homo sapiens
Other Product Names
MDFI, inhibitor of MyoD family a, OTTHUMP00000196414, OTTHUMP00000016375, I-mfa, I-MF, MyoD family inhibitor, MDFI
Tested Applications
WB
Physical Properties
Liquid
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