CARS Antibody
Product Specifications
Background
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
833
Swiss Prot
P49589
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 469-748 of human CARS (NP_001742.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 85kDa
Fragment
IgG
Symbol
CARS
Positive Control 2
HeLa
Positive Control 3
BxPC-3
Positive Control 4
MCF7
Positive Control 5
Mouse liver
Positive Control 6
Mouse skeletal muscle
NCBI Official Name
Cysteinyl-tRNA synthetase
NCBI Organism
Homo sapiens
Other Product Names
CARS, CARS1, CYSRS, MGC:11246
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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