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TCAP Antibody

Product Specifications

Background

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

NCBI Gene ID

8557

Swiss Prot

O15273

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_003664.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Mouse heart

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=15-074

Calculated Molecular Weight

Observed: 19kDa

Fragment

IgG

Symbol

TCAP

Positive Control 2

Mouse skeletal muscle

NCBI Official Name

Titin-cap

NCBI Organism

Homo sapiens

Other Product Names

TCAP, CMD1N, LGMD2G, T-cap, TELE, telethonin

Tested Applications

WB, IF

Physical Properties

Liquid

Curated Selection

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