TCAP Antibody
Product Specifications
Background
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
NCBI Gene ID
8557
Swiss Prot
O15273
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_003664.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Mouse heart
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 19kDa
Fragment
IgG
Symbol
TCAP
Positive Control 2
Mouse skeletal muscle
NCBI Official Name
Titin-cap
NCBI Organism
Homo sapiens
Other Product Names
TCAP, CMD1N, LGMD2G, T-cap, TELE, telethonin
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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