SUFU Antibody
Product Specifications
Background
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
51684
Swiss Prot
Q9UMX1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_057253.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
Mouse testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54kDa
Fragment
IgG
Symbol
SUFU
Positive Control 2
Rat kidney
NCBI Official Name
Suppressor of fused homolog (Drosophila)
NCBI Organism
Homo sapiens
Other Product Names
SUFUH, SUFUXL, PRO1280, CFL, SUFUH
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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