DRD4 Antibody
Product Specifications
Background
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
NCBI Gene ID
1815
Swiss Prot
P21917
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP_000788.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Symbol
DRD4
Positive Control 2
Rat brain
NCBI Official Name
Dopamine receptor D4
NCBI Organism
Homo sapiens
Other Product Names
DRD4, dopamine receptor D4, D4DR, D (2C) dopamine receptor, dopamine D4 receptor, seven transmembrane helix receptor
Tested Applications
WB, IHC
Physical Properties
Liquid
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