PDK4 Antibody
Product Specifications
Background
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
NCBI Gene ID
5166
Swiss Prot
Q16654
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 102-411 of human PDK4 (NP_002603.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 46kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PDK4
Positive Control 2
HT-1080
Positive Control 3
Mouse uterus
Positive Control 4
Mouse heart
Positive Control 5
Mouse skeletal muscle
Positive Control 6
Rat skeletal muscle
NCBI Official Name
Pyruvate dehydrogenase kinase, isozyme 4
NCBI Organism
Homo sapiens
Other Product Names
PDK4, FLJ40832, PDHK4
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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