PARVB Antibody
Product Specifications
Background
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
29780
Swiss Prot
Q9HBI1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human PARVB (NP_037459.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PARVB
Positive Control 2
A375
Positive Control 3
HeLa
Positive Control 4
Mouse heart
Positive Control 5
Rat heart
NCBI Official Name
Parvin, beta
NCBI Organism
Homo sapiens
Other Product Names
PARVB, CGI-56
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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