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BDNF Antibody

Product Specifications

Background

This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

NCBI Gene ID

627

Swiss Prot

P23560

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-247 of human BDNF (NP_733928.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Growth Factors, Neuroscience, Obesity

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 14kDa

Fragment

IgG

Symbol

BDNF

Positive Control 2

SW480

Positive Control 3

Mouse kidney

Positive Control 4

Mouse brain

Positive Control 5

Rat brain

NCBI Official Name

Brain-derived neurotrophic factor

NCBI Organism

Homo sapiens

Other Product Names

BDNF , brain-derived neurotrophic factor, MGC34632, neurotrophin

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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