BFSP2 Antibody
Product Specifications
Background
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF) . Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
NCBI Gene ID
8419
Swiss Prot
Q13515
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 116-415 of human BFSP2 (NP_003562.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
Mouse eye
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 46kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
BFSP2
NCBI Official Name
Beaded filament structural protein 2
NCBI Organism
Homo sapiens
Other Product Names
CP47, CP49, CTRCT12, LIFL-L, PHAKOSIN, phakinin, 49 kDa cytoskeletal protein, beaded filament protein CP49, beaded filament structural protein 2, phakinin, bfps2, Cytoskeletal protein, 49-kD, lens fiber cell beaded filament protein CP 47, lens fiber cell beaded filament protein CP 49, lens intermediate filament-like light
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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